Motor Innervation of Muscle

The Motor Innervation of a Triply Innervated Crustacean Muscle

Beta1 integrins in muscle, but not in motor neurons, are required for skeletal muscle innervation.

In vitro studies have provided evidence that beta1 integrins in motor neurons promote neurite outgrowth, whereas beta1 integrins in myotubes regulate acetylcholine receptor (AChR) clustering. Surprisingly, using genetic studies in mice, we show here that motor axon outgrowth and neuromuscular junction (NMJ) formation in large part are unaffected when the integrin beta1 gene (Itgb1) is inactivat...

Sources of the motor and somatic sensory innervation of the trapezius muscle in the rat

The study was carried out on nine sexually mature male rats of the Wistar breed weighing approximately 250 g each. Animals were anaesthetized with thiopental sodium injected intraperitoneally (30 mg/kg of body weight). The animals were then injected with Fast Blue tracer into the right trapezius muscle. After a survival period of five weeks the rats were transcardially perfused with buffered pa...

Motor innervation of the muscle spindle: the contribution of bernhard katz.

JJEE BB CC llaa ssss iicc ss JEB Classics is an occasional column, featuring historic publications from The Journal of Experimental Biology. These articles, written by modern experts in the field, discuss each classic paper’s impact on the field of biology and their own work. A PDF of the original paper is available from the JEB Archive (http://jeb.biologists.org/). MOTOR INNERVATION OF THE MUS...

The innervation and organization of motor units in a series-fibered human muscle: the brachioradialis.

We studied the innervation and organization of motor units in the brachioradialis muscle of 25 normal human subjects. We recorded intramuscular EMG signals at points separated by 15 mm along the proximodistal muscle axis during moderate isometric contractions, identified from 27 to 61 (mean 39) individual motor units per subject using EMG decomposition, and estimated the locations of the endpla...